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The liver span is a measurement performed during physical examination to determine the size of the liver and identify possible hepatomegaly.. It is the distance between the lower border of the liver in the mid-clavicular line obtained by palpation, and the upper border of the liver in the mid-clavicular line detected by percussion (the upper border of the liver lies behind the ribs and can not ...
The liver, viewed from above, showing the left and right lobes separated by the falciform ligament. The liver is a dark reddish brown, wedge-shaped organ with two lobes of unequal size and shape.
Liver function tests (LFTs or LFs), also referred to as a hepatic panel or liver panel, are groups of blood tests that provide information about the state of a patient's liver. [1] These tests include prothrombin time (PT/INR), activated partial thromboplastin time (aPTT), albumin , bilirubin (direct and indirect), and others.
Abdominal ultrasonography of the liver, as a sagittal plane through the midclavicular line, with some standard measurements [2] Right lobe of the liver at the midclavicular line at ages 0 to 7 [16] Suspicion of hepatomegaly indicates a thorough medical history and physical examination, wherein the latter typically includes an increased liver span.
Liver size can be enlarged, normal, or shrunken in people with cirrhosis. [35] As the disease progresses, the liver will typically shrink due to the result of scarring. [36] Jaundice is the yellowing of the skin. It can additionally cause yellowing of mucous membranes notably of the white of the eyes.
The liver scratch test (also known as Lazar's test) is a technique used by medical professionals during a physical exam to locate the inferior border of the liver in order to approximate the size of a patient's liver.
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The proportion of AST to ALT in hepatocytes is about 2.5:1, but because AST is removed from serum by the liver sinusoidal cells twice as quickly (serum half-life t 1/2 = 18 hr) compared to ALT (t 1/2 = 36 hr), so the resulting serum levels of AST and ALT are about equal in healthy individuals, resulting in a normal AST/ALT ratio around 1.