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At higher doses, niacin has been used to treat high cholesterol and triglyceride levels, since it can help lower LDL (“bad”) cholesterol and raise levels of HDL (“good”) cholesterol.
The researcher also said those taking niacin for the cholesterol-lowering effects would find better treatments elsewhere, as previous research has shown niacin to be less effective than other ...
The results of the AIM-HIGH trial, published in 2011, showed that adding niacin to statin therapy did not significantly reduce the risk of cardiovascular events compared to statin therapy alone: [1] Primary Endpoint: There was no significant difference in the incidence of major cardiovascular events between the niacin and placebo groups (16.4% ...
Systematic reviews found no effect of prescription nicotinic acid on all-cause mortality, cardiovascular mortality, myocardial infarctions, nor fatal or non-fatal strokes despite raising HDL cholesterol in patients already taking statins. [13] [45] Reported side effects include an increased risk of new-onset type 2 diabetes. [15] [17] [18] [46]
Julia Kim, 64, an IT specialist from Boston, began taking a statin more than 30 years ago because of a family history of high cholesterol. But six months ago, tired of having to take the drug and ...
In the US, niacin is also available as a dietary supplement at 500 to 1,000 mg/tablet. Niacin has sometimes been used in combination with other lipid-lowering medications. [37] Systematic reviews found no effect of niacin on cardiovascular disease or death, in spite of raising high-density lipoprotein (HDL) cholesterol.