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Bioavailability Definition. When a substance such as a medicine or supplement enters your system, the portion of the total substance introduces which can effectively create a response determines that substance’s bioavailability. The bioavailability of a substance can fluctuate, depending on the route of administration.
The meaning of BIOAVAILABILITY is the degree and rate at which a substance (such as a drug) is absorbed into a living system or is made available at the site of physiological activity.
Bioavailability refers to the extent a substance or drug becomes completely available to its intended biological destination(s). More accurately, bioavailability is a measure of the rate and fraction of the initial dose of a drug that successfully reaches either; the site of action or the bodily fluid domain from which the drug's intended ...
In pharmacology, bioavailability is a subcategory of absorption and is the fraction (%) of an administered drug that reaches the systemic circulation. [1] By definition, when a medication is administered intravenously, its bioavailability is 100%.
The term bioavailability refers to the fraction of compound that is actively available within the body; that is, bioavailability of a nutrient can be defined as the fraction of the ingested nutrient that actually reaches the systemic (blood) circulation in an active form (Parada and Aguilera, 2007).
Bioavailability is a concept which applies to nutrients and drugs which pass through first-pass metabolism, i.e. orally (and to some extent nasally) consumed substances. Anything absorbed in the gut first passes through the liver before reaching the rest of the circulation, and both the gut and liver may metabolise it to some extent.
Bioavailability refers to the proportion of a nutrient or medication that enters the bloodstream and is available for the body to use. Enhancing bioavailability can significantly improve the effectiveness of supplements and pharmaceuticals.
Bioavailability is a key step in ensuring bioefficacy of bioactive food compounds or oral drugs. Bioavailability is a complex process involving several different stages: liberation, absorption, distribution, metabolism and elimination phases (LADME).
Bioavailability refers to the proportion of a nutrient or bioactive compound that is absorbed and utilized by the body after ingestion. It highlights how effectively nutrients are extracted from food and made available for physiological functions, which can be influenced by factors like digestion, nutrient interactions, and food processing methods.
Definition. Bioavailability refers to the proportion of a drug or other substance that enters the systemic circulation when introduced into the body and is available for therapeutic effect. It is a critical parameter in drug development, influencing dosing regimens and overall drug efficacy.