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Tuberculosis (TB) vaccines are vaccinations intended for the prevention of tuberculosis. Immunotherapy as a defence against TB was first proposed in 1890 by Robert Koch . [ 1 ] As of 2021, the only effective tuberculosis vaccine in common use is the Bacillus Calmette-Guérin (BCG) vaccine, first used on humans in 1921.
The Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). [9] It is named after its inventors Albert Calmette and Camille Guérin. [10] [11] In countries where tuberculosis or leprosy is common, one dose is recommended in healthy babies as soon after birth as possible. [9]
As with all medications, vaccines are continually monitored for safety, and like any medication, vaccines can cause side effects. The side effects of vaccination are typically minor and go away within a few days. There is a risk that the child could have a severe allergic reaction, but these reactions are rare.
The only vaccine, called the BCG vaccine, is used mainly in high-risk areas to protect babies from one form of the disease. Century-old TB vaccine may work better if given in a new way Skip to ...
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The vaccine completed a Phase I double-blind randomized controlled clinical trial that demonstrated that rBCG30 was safe and immunogenic; during nine months of follow-up, rBCG30, but not BCG, induced significantly increased Antigen 85B-specific immune responses in eight immunological assays (blood lymphocyte proliferation, antibody responses by ELISA, interferon-gamma producing CD4+ and CD8+ T ...
BCG vaccine is given at birth to "children born in areas of the country where there are high numbers of TB cases" and "children whose parents or grandparents were born in a country with many cases of TB." [39] Hepatitis B vaccine is given at birth to "babies born to mothers who have hepatitis B". [39]
Tuberculosis (TB), also known colloquially as the "white death", or historically as consumption, [7] is a contagious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. [1] Tuberculosis generally affects the lungs, but it can also affect other parts of the body. [1]