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PMAT may refer to: Plasma membrane monoamine transporter (PMAT) Four phases of mitosis: prophase, metaphase, anaphase, and telophase: Prophase: Chromatin into chromosomes, the nuclear envelope breaks down, chromosomes attach to spindle fibers by their centromeres. Metaphase: Chromosomes line up along the metaphase plate (center of the cell).
PMAT has 530 amino acid residues with a predicted molecular weight of 58kD, 11 transmembrane segments, an extracellular C-terminus, and an intracellular N-terminus. [ 15 ] [ 12 ] [ 17 ] It has several phosphorylation sites and a potential glycosylation site, and its first 6 transmembrane domains are suspected to be important for substrate ...
It can also happen during mitotic division, [1] which may result in loss of heterozygosity. Crossing over is important for the normal segregation of chromosomes during meiosis. [ 2 ] Crossing over also accounts for genetic variation, because due to the swapping of genetic material during crossing over, the chromatids held together by the ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 16 January 2025. Cell division producing haploid gametes For the figure of speech, see Meiosis (figure of speech). For the process whereby cell nuclei divide to produce two copies of themselves, see Mitosis. For excessive constriction of the pupils, see Miosis. For the parasitic infestation, see Myiasis ...
In general, nondisjunction can occur in any form of cell division that involves ordered distribution of chromosomal material. Higher animals have three distinct forms of such cell divisions: Meiosis I and meiosis II are specialized forms of cell division occurring during generation of gametes (eggs and sperm) for sexual reproduction, mitosis is the form of cell division used by all other cells ...
During the phase of meiosis labeled “interphase s” in the meiosis diagram there is a round of DNA replication, so that each of the chromosomes initially present is now composed of two copies called chromatids. These chromosomes (paired chromatids) then pair with the homologous chromosome (also paired chromatids) present in the same nucleus ...
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Homologous recombination is the principal mechanism of DNA repair acting during meiosis. From the leptotene to early pachytene stages of meiosis exogenous damage triggered the massive presence of gamma H2AX (which forms when DNA double-strand breaks appear), H2AX was present throughout the nucleus, and this was associated with DNA repair ...