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  2. Acanthosis nigricans - Wikipedia

    en.wikipedia.org/wiki/Acanthosis_nigricans

    Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [ 2 ] such as the posterior and lateral folds of the neck , the armpits , groin , navel , forehead and other areas.

  3. Crouzonodermoskeletal syndrome - Wikipedia

    en.wikipedia.org/wiki/Crouzonodermoskeletal_syndrome

    Crouzonodermoskeletal syndrome is a disorder characterized by the premature joining of certain bones of the skull (craniosynostosis) during development and a skin condition called acanthosis nigricans. [1] Some of the signs and symptoms of Crouzonodermoskeletal syndrome are similar to those seen with Crouzon syndrome.

  4. Severe achondroplasia with developmental delay and acanthosis ...

    en.wikipedia.org/wiki/Severe_Achondroplasia_with...

    Acanthosis nigricans is a skin condition in which areas of the skin is of a dark and velvety discoloration, often seen in the body folds and creases such as the armpits, groin, and neck. [6] Within those affected by SADDAN, acanthosis nigricans develops early on, usually in infancy or early childhood. [4]

  5. Acanthosis nigricans-muscle cramps-acral enlargement syndrome

    en.wikipedia.org/wiki/Acanthosis_nigricans...

    Acanthosis nigricans-muscle cramps-acral enlargement syndrome, also known as Acanthosis nigricans-insulin resistance-muscle cramps-acral enlargement syndrome is an extremely rare genetic disorder which is characterized by the appearance of acanthosis nigricans, insulin resistance, muscle cramps of severe intensity, and acral hypertrophy ...

  6. HAIR-AN syndrome - Wikipedia

    en.wikipedia.org/wiki/HAIR-AN_syndrome

    Acanthosis nigricans The HAIR-AN syndrome is a rare subtype of polycystic ovary syndrome (PCOS) characterized by hyperandrogenism (HA), insulin resistance (IR) and acanthosis nigricans (AN).

  7. Hyperpigmentation - Wikipedia

    en.wikipedia.org/wiki/Hyperpigmentation

    Acanthosis nigricans—hyperpigmentation of intertriginous areas associated with insulin resistance. Melasma, also known as 'chloasma' or the “mask of pregnancy,” when it occurs in pregnant women.— It is a common skin problem that causes dark discolored patchy hyperpigmentation.

  8. Rabson–Mendenhall syndrome - Wikipedia

    en.wikipedia.org/wiki/Rabson–Mendenhall_syndrome

    A skin abnormality known as acanthosis nigricans, which involves a discoloration (hyperpigmentation) and "velvety" thickening (hyperkeratosis) of the skin around skin fold regions of the neck, groin and under arms is also a common symptom. [1] Symptoms will negatively impact the daily life of the patient, and will persist until treated.

  9. Leser–Trélat sign - Wikipedia

    en.wikipedia.org/wiki/Leser–Trélat_sign

    In some cases, paraneoplastic acanthosis nigricans (35% of patients), florid cutaneous papillomatosis, ichthyosis acquisita (acquired hypertrichosis lanuginosa), Cowden syndrome, tylosis, acrokeratosis paraneoplastica of Bazex or tripe palms accompany the sign of Leser–Trélat.