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Uterus of a dog. Pyometra in a dog. The most obvious symptom of open pyometra is a discharge of pus from the vulva in a female that has recently been in heat. However, symptoms of closed pyometra are less obvious. Symptoms of both types include vomiting, loss of appetite, depression, and increased drinking and urinating. [1]
In male dogs, the tumor affects the penis and foreskin. In female dogs, it affects the vulva. Rarely, the mouth or nose are affected. [8] The tumor often has a cauliflower-like appearance. Signs of genital TVT include a discharge from the prepuce and in some cases urinary retention caused by blockage of the urethra. [9]
Female dogs are at risk for endometritis and pyometra in the postpartum period and after estrus or vaginitis. Signs and symptoms include fever, lethargy, loss of appetite, excessive thirst, restlessness, a foul smelling vaginal discharge which may or may not be bloody, infertility, or they may be asymptomatic.
Ovulation occurs 24–48 hours after the luteinizing hormone peak, which occurs around the fourth day of estrus; therefore, this is the best time to begin breeding. Proestrus bleeding in dogs is common and is believed to be caused by diapedesis of red blood cells from the blood vessels due to the increase of the estradiol-17β hormone. [20]
Infection is usually in the nasal cavity. Typical signs in dogs include sneezing, nasal discharge, bleeding from the nose, and ulcerations of the nose. [23] Pythiosis is a disease caused by a water mould of the genus Pythium, P. insidiosum. It occurs primarily in dogs and horses, but can also affect humans.
A list of possible symptoms a dog with Lepto may exhibit are fever, sore muscles, reluctance to move, shivering, weakness, a runny nose, increased thirst and urination and a lack of appetite.
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Hemangiosarcomas form from the cells lining blood vessels (endothelial cells) and can occur all over the body. These tumors can develop on the skin, subcutaneously, or on a blood vessel within an organ and are highly malignant. The tumors are most fatal when they rupture, causing the dog to suffer from severe loss of blood, or hypovolemia. [6]