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The nucleoid (meaning nucleus-like) is an irregularly shaped region within the prokaryotic cell that contains all or most of the genetic material. [ 1 ] [ 2 ] [ 3 ] The chromosome of a typical prokaryote is circular , and its length is very large compared to the cell dimensions, so it needs to be compacted in order to fit.
Diagram of a prokaryotic cell, a bacterium with a flagellum. A prokaryote (/ p r oʊ ˈ k ær i oʊ t,-ə t /; less commonly spelled procaryote) [1] is a single-celled organism whose cell lacks a nucleus and other membrane-bound organelles. [2]
Cells are broadly categorized into two types: eukaryotic cells, which possess a nucleus, and prokaryotic cells, which lack a nucleus but have a nucleoid region. Prokaryotes are single-celled organisms such as bacteria, whereas eukaryotes can be either single-celled, such as amoebae, or multicellular, such as some algae, plants, animals, and fungi.
Although prokaryotic organisms do not possess a membrane-bound nucleus like eukaryotes, they do contain a nucleoid region in which the main chromosome is found. Extrachromosomal DNA exists in prokaryotes outside the nucleoid region as circular or linear plasmids.
It is present in most cells, with a few exceptions, for example, red blood cells. Histones are responsible for the first and most basic unit of chromosome organization, the nucleosome . Eukaryotes ( cells with nuclei such as those found in plants, fungi, and animals) possess multiple large linear chromosomes contained in the cell's nucleus.
The cell nucleus (from Latin nucleus or nuculeus ' kernel, seed '; pl.: nuclei) is a membrane-bound organelle found in eukaryotic cells. Eukaryotic cells usually have a single nucleus, but a few cell types, such as mammalian red blood cells , have no nuclei , and a few others including osteoclasts have many .
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Prokaryotic cells have entirely different structures for organizing their DNA (the prokaryotic chromosome equivalent is called a genophore and is localized within the nucleoid region). The overall structure of the chromatin network further depends on the stage of the cell cycle.