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Malaria is presently endemic in a broad band around the equator, in areas of the Americas, many parts of Asia, and much of Africa; in Sub-Saharan Africa, 85–90% of malaria fatalities occur. [221] An estimate for 2009 reported that countries with the highest death rate per 100,000 of population were Ivory Coast (86.15), Angola (56.93) and ...
The history of malaria extends from its prehistoric origin as a zoonotic disease in the primates of Africa through to the 21st century. A widespread and potentially lethal human infectious disease, at its peak malaria infested every continent except Antarctica . [ 1 ]
In West Africa an HLA class I antigen (HLA Bw53) and an HLA class II haplotype (DRB1*13OZ-DQB1*0501) are independently associated with protection against severe malaria. [60] However, HLA correlations vary, depending on the genetic constitution of the polymorphic malaria parasite, which differs in different geographic locations.
Of the 12 countries that carry about 70% of the global burden of malaria, 11 are in Africa and the other is India. Children under 5 constituted 80% of the 580,000 malaria deaths recorded in Africa ...
The infection is most prevalent in Africa, where 94% of malaria deaths occur. Children under five years of age are most affected, and 67% of malaria deaths occurred in this age group. 80% of the infection is found in Sub-Saharan Africa, 7% in South-East Asia, and 2% in the Eastern Mediterranean.
The CDC of Africa also responded and said that they were investigating with the government of the Democratic Republic of the Congo on this issue. [7] [19] While the disease was unidentified, on 5 December 2024, Hong Kong tightened health screenings at airports and at other boundary control points in response to the outbreak. [20]
Blackwater fever is a serious complication of malaria, but cerebral malaria has a higher mortality rate. Blackwater fever is much less common today than it was before 1950. [4] It may be that quinine plays a role in triggering the condition, [5] and this drug is no longer commonly used for malaria prophylaxis. Quinine remains important for ...
The African Leaders Malaria Alliance (ALMA) is an intergovernmental organization dedicated to ending malaria deaths which became operational during the 64th United Nations General Assembly on September 23, 2009.