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Microfluidics refers to a system that manipulates a small amount of fluids (10 −9 to 10 −18 liters) using small channels with sizes of ten to hundreds of micrometres. It is a multidisciplinary field that involves molecular analysis, molecular biology , and microelectronics . [ 1 ]
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Microfluidic devices make possible the study of a single cell to a few hundred cells in a 3D environment. Comparatively, macroscopic 2D cultures have 10 4 to 10 7 cells on a flat surface. [10] Microfluidics also allow for chemical gradients, the continuous flow of fresh media, high through put testing, and direct output to analytical ...
Microfluidics refers to the flow of fluid in channels or networks with at least one dimension on the micron scale. [1] [2] In open microfluidics, also referred to as open surface microfluidics or open-space microfluidics, at least one boundary confining the fluid flow of a system is removed, exposing the fluid to air or another interface such as a second fluid.
Microfluidics deals with the behavior, precise control and manipulation of fluids that are geometrically constrained to a small, typically sub-millimeter, scale. Typically, micro means one of the following features: small volumes(nl, pl, fl) small size; low energy consumption
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Droplet formation using a T-junction. [9] Formation of droplets with a T junction microfluidic device. The break off of a droplet comes from a drop in pressure as a drop emerges. [10] Cross-flowing is a passive formation method that involves the continuous and aqueous phases running at an angle to each other. [9]
A microvalve is a microscale valve, i.e. a microfluidic two-port component that regulates the flow between two fluidic ports. Microvalves are basic components in microfluidic devices, such as labs-on-a-chip, where they are used to control the fluidic transport.