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Spherocytosis is the presence of spherocytes in the blood, i.e. erythrocytes (red blood cells) that are sphere-shaped rather than bi-concave disk shaped as normal. Spherocytes are found in all hemolytic anemias to some degree.
MCHC can be normal even when hemoglobin production is decreased (such as in iron deficiency) due to a calculation artifact. MCHC can be elevated ("hyperchromic") in hereditary spherocytosis , sickle cell disease and homozygous hemoglobin C disease , depending upon the hemocytometer.
In patients with anemia, it is the MCV measurement that allows classification as either a microcytic anemia (MCV below normal range), normocytic anemia (MCV within normal range) or macrocytic anemia (MCV above normal range). Normocytic anemia is usually deemed so because the bone marrow has not yet responded with a change in cell volume.
A human peripheral blood smear; NRBCs are visible as larger cells with dark centers.. A nucleated red blood cell (NRBC), also known by several other names, is a red blood cell that contains a cell nucleus.
Neutrophil to Lymphocyte ratio was first demonstrated as useful parameter after a correlation of a relationship between the neutrophil lymphocyte ratio to reactions of the immune response was noted.
Normal: AHI<5; Mild sleep apnea: 5≤AHI<15; Moderate sleep apnea: 15≤AHI<30; Severe sleep apnea: AHI≥30; For children, because of their different physiology, an AHI in excess of 1 is considered abnormal. Underage pediatric patients presenting with AHI of 2 or greater will often be referred for treatment. [3]