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It has been demonstrated that high concentrations of oxygen lead to generation of oxygen free radicals, which have a role in reperfusion injury after asphyxia. [4] Research by Ola Didrik Saugstad and others led to new international guidelines on newborn resuscitation in 2010, recommending the use of normal air instead of 100% oxygen. [5] [6]
There has long been a debate over whether newborn infants with birth asphyxia should be resuscitated with 100% oxygen or normal air. [29] It has been demonstrated that high concentrations of oxygen lead to generation of oxygen free radicals, which have a role in reperfusion injury after asphyxia. [30]
There are few side effects, other than vomiting, with short-term use. [1] [2] With long-term use anemia or numbness may occur. [2] It should always be given with at least 21% oxygen. [2] It is not recommended in people with a bowel obstruction or pneumothorax. [2] Use in the early part of pregnancy is not recommended. [1]
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The use of ergometrine, on the other hand, is associated with nausea or vomiting and hypertension. [4] Breastfeeding soon after birth stimulates oxytocin which increases uterine tone, and through physical mechanisms uterine massage (targeting the fundus) also causes uterine contractions.
It has been demonstrated that high concentrations of oxygen lead to generation of oxygen free radicals, which have a role in reperfusion injury after asphyxia. [12] Clinical trial evidence suggests that resuscitation using air probably reduces the risk of death [ 13 ] and the 2010 ILCOR guidelines recommend the use of normal air rather than 100 ...
The EXIT procedure, or ex utero intrapartum treatment procedure, is a specialized surgical delivery procedure used to deliver babies who have airway compression. [1] Causes of airway compression in newborn babies result from a number of rare congenital disorders, including bronchopulmonary sequestration, congenital cystic adenomatoid malformation, mouth or neck tumor such as teratoma, and lung ...
1. Gas source: An oxygen blender connected to a source of oxygen and compressed air is used to supply an appropriate concentration of inspired oxygen . The humidified blended oxygen is then circulated through corrugated tubing. 2. Pressure generator: Pressure in the bubble CPAP system is created by placing the distal expiratory tubing in water.