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  2. Caffeinism - Wikipedia

    en.wikipedia.org/wiki/Caffeinism

    Death can occur as a result of caffeine overdose. [10] [11] The LD 50 of caffeine in humans is dependent on individual sensitivity, but is estimated to be 150–200 milligrams per kilogram of body mass (75–100 cups of coffee for a 70 kilogram adult). [12]

  3. Nicotine poisoning - Wikipedia

    en.wikipedia.org/wiki/Nicotine_poisoning

    The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...

  4. Substance use disorder - Wikipedia

    en.wikipedia.org/wiki/Substance_use_disorder

    "Substance use pertains to using select substances such as alcohol, tobacco, illicit drugs, etc. that can cause dependence or harmful side effects."On the other hand, substance abuse is the use of drugs such as prescriptions, over-the-counter medications, or alcohol for purposes other than what they are intended for or using them in excessive ...

  5. Dark roasted and dangerous: Everything you should know ... - AOL

    www.aol.com/news/caffeine-intoxication-prevent...

    Caffeine intoxication occurs when a person has dangerously high levels of caffeine in their system, and symptoms can include seizures and trouble breathing. Dark roasted and dangerous: Everything ...

  6. Doctor explains teen's caffeine overdose death: 'A perfect ...

    www.aol.com/lifestyle/2017-05-17-doctor-explains...

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  7. Nicotine dependence - Wikipedia

    en.wikipedia.org/wiki/Nicotine_dependence

    A National Institute on Drug Abuse video entitled Anyone Can Become Addicted to Drugs. [21]Nicotine dependence is defined as a neurobiological adaptation to repeated drug exposure that is manifested by highly controlled or compulsive use, the development of tolerance, experiencing withdrawal symptoms upon cessation including cravings, and an inability to quit despite harmful effects. [9]

  8. Caffeine can kill: The dangers of energy drinks - AOL

    www.aol.com/article/lifestyle/2017/05/24/...

    It's now clear that under no circumstances should children or adolescents be given access to these beverages.

  9. Substance intoxication - Wikipedia

    en.wikipedia.org/wiki/Substance_intoxication

    Contact high is a phenomenon that occurs in otherwise sober people who experience a drug-like effect just by coming into contact with someone who is under the influence of a psychoactive drug. In a similar way to the placebo effect, a contact high may be caused by classical conditioning as well as by the physical and social setting. [8] [9]