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NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10 is an enzyme that in humans is encoded by the NDUFA10 gene. [ 5 ] [ 6 ] The NDUFA10 protein is a subunit of NADH dehydrogenase (ubiquinone) , which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain .
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9 is an enzyme that in humans is encoded by the NDUFA9 gene. [5] [6] [7] The NDUFA9 protein is a subunit of NADH:ubiquinone oxidoreductase (Complex I of the electron transport chain), which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain.
The NDUFA13 gene is located on the p arm of chromosome 19 in position 13.2 and spans 11,995 base pairs. [8] The gene produces a 17 kDa protein composed of 144 amino acids. [11] [12] NDUFA13 is a subunit of the enzyme NADH dehydrogenase (ubiquinone), the largest of the respiratory complexes.
Respiratory complex I, EC 7.1.1.2 (also known as NADH:ubiquinone oxidoreductase, Type I NADH dehydrogenase and mitochondrial complex I) is the first large protein complex of the respiratory chains of many organisms from bacteria to humans.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 is an enzyme that in humans is encoded by the NDUFA12 gene. [ 5 ] [ 6 ] [ 7 ] The NDUFA12 protein is a subunit of NADH dehydrogenase (ubiquinone) , which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain .
[5] [6] [7] NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10 is an accessory subunit of the NADH dehydrogenase (ubiquinone) complex, located in the mitochondrial inner membrane. It is also known as Complex I and is the largest of the five complexes of the electron transport chain. [8]
The structure is L-shaped with a long, hydrophobic transmembrane domain and a hydrophilic domain for the peripheral arm that includes all the known redox centres and the NADH binding site. MT-ND5 and the rest of the mitochondrially encoded subunits are the most hydrophobic of the subunits of Complex I and form the core of the transmembrane region.
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 is a protein that in humans is encoded by the NDUFA2 gene. [ 5 ] [ 6 ] The NDUFA2 protein is a subunit of NADH dehydrogenase (ubiquinone) , which is located in the mitochondrial inner membrane and is the largest of the five complexes of the electron transport chain . [ 7 ]