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Participants were divided into two groups—one was given a placebo, while the other was given a vitamin D supplement of 60,000 IU a month (which averages out to about 2,000 IU a day) for up to ...
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They also had a serum 25-hydroxy vitamin D level between 10 and 30 ng/mL, which indicates either “insufficient” vitamin D levels (below 30/mL) or vitamin D deficiency (below 20 ng/mL).
[75] [76] A review did not find any effect from supplementation on the rates of non-skeletal disease, other than a tentative decrease in mortality in the elderly. [77] Vitamin D supplements do not alter the outcomes for myocardial infarction, stroke or cerebrovascular disease, cancer, bone fractures or knee osteoarthritis. [10] [78]
Vitamin D 2, or ergocalciferol, is obtained from D 2 supplements or fortified food sources. [3] These two forms of vitamin D are metabolized in the liver and stored as 25-hydroxyvitamin D. [ 4 ] Before biological use, the storage form must be converted into an active form.
Ergocalciferol may be used as a vitamin D supplement, whereas cholecalciferol (vitamin D 3) is produced naturally by the skin when exposed to ultraviolet light. [15] Ergocalciferol (D 2 ) and cholecalciferol (D 3 ) are considered to be equivalent for vitamin D production, as both forms appear to have similar efficacy in ameliorating rickets ...