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Additional treatment options include the use of prokinetic drugs such as 5-HT 4 receptor agonists or motilin agonists to extend the SIBO free period after treatment with an elemental diet or antibiotics. [37] [non-primary source needed] A diet void of certain foods that feed the bacteria can help alleviate the symptoms. [38]
Clostridioides difficile, also known more commonly as C. diff, accounts for 10 to 20% of antibiotic-associated diarrhea cases, because the antibiotics administered for the treatment of certain disease processes such as inflammatory colitis also inadvertently kill a large portion of the gut flora, the normal flora that is usually present within the bowel.
SIBO causes abdominal discomfort and symptoms like excess gas, bloating, and constipation. Treatments can help with symptom management and should be tailored to the individual.
The United Kingdom's Health Protection Agency has stated that "most isolates with NDM-1 enzyme are resistant to all standard intravenous antibiotics for treatment of severe infections." [100] On 26 May 2016, an E. coli "superbug" was identified in the United States resistant to colistin, "the last line of defence" antibiotic.
In humans, oral immunoglobulins may improve function in the gastrointestinal (GI) tract. [6] Conditions like HIV-enteropathy, IBS-D (irritable bowel syndrome with diarrhea), SIBO (small intestine bacterial overgrowth), recurrent C. difficile infection-associated diarrhea and post-infectious IBS-D often limit or impair the body's ability to absorb and digest select nutrients including water. [5]
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