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Fipronil is a broad-spectrum insecticide that belongs to the phenylpyrazole insecticide class. [3] Fipronil disrupts the insect central nervous system by blocking the ligand-gated ion channel of the GABA A receptor (IRAC group 2B) and glutamate-gated chloride (GluCl) channels. This causes hyperexcitation of contaminated insects' nerves and muscles.
Phenylpyrazole insecticides function by blocking GABA-gated chloride channels in insects (IRAC group 2B). [1] Mammals do not have this type of chloride channel, making them much less susceptible to its effects. However, they do have the capacity to disrupt epithelial cells in the human intestine and adversely impact human health. [2]
This is a list of insecticides. These are chemical compounds which have been registered as insecticides . The names on the list are the ISO common name for the active ingredient which is formulated into the branded product sold to end-users. [ 1 ]
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