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The cause and mechanism of bipolar disorder is not yet known, and the study of its biological origins is ongoing. Although no single gene causes the disorder, a number of genes are linked to increase risk of the disorder, and various gene environment interactions may play a role in predisposing individuals to developing bipolar disorder.
The causes of bipolar disorder likely vary between individuals and the exact mechanism underlying the disorder remains unclear. [52] Genetic influences are believed to account for 73–93% of the risk of developing the disorder indicating a strong hereditary component. [9] The overall heritability of the bipolar spectrum has been estimated at 0 ...
Bipolar disorder has one of the highest rates of suicide amongst psychiatric disorders, as well as high comorbidity rates with alcohol and substance use disorders. [2] Bipolar disorder has a genetic component. [3] This means that the sequence of nucleotides in DNA contains information that can lead to bipolar disorder in individuals ...
Older twin studies suggest that 79 percent to 93 percent of the risk of bipolar disorder is genetic. ... While environmental factors aren’t thought to cause bipolar disorder, they may trigger an ...
The more extreme form of mania can cause highly noticeable problems at work, school and at home and in social situations, according to Mayo. ... while bipolar II disorder shares more genetic ...
A systematic comparative analysis of shared and unique genetic factors highlighted key gene sets and molecular processes underlying six major neuropsychiatric disorders: attention deficit hyperactivity disorder, anxiety disorders, autistic spectrum disorders, bipolar disorder, major depressive disorder, and schizophrenia. [9]