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A commonly used surrogate marker for the estimation of creatinine clearance is the Cockcroft–Gault (CG) formula, which in turn estimates GFR in ml/min: [21] It is named after the scientists, the asthmologist Donald William Cockcroft (b. 1946) and the nephrologist Matthew Henry Gault (1925–2003), who first published the formula in 1976, and ...
The above formula only applies for GFR calculation when it is equal to the clearance rate. The normal range of GFR, adjusted for body surface area , is 100–130 average 125 (mL/min)/(1.73 m 2 ) in men and 90–120 (mL/min)/(1.73 m 2 ) in women younger than the age of 40.
MDCalc is a free online medical reference for healthcare professionals that provides point-of-care clinical decision-support tools, including medical calculators, scoring systems, and algorithms. [1] MDCalc is also a mobile and web app. [ 2 ] The decision-support tools are based on published clinical research, [ 3 ] and MDCalc’s content is ...
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Formulas such as the Cockcroft and Gault formula and the MDRD formula (see Renal function) try to adjust for these variables. Cystatin C has a low molecular weight (approximately 13.3 kilodaltons), and it is removed from the bloodstream by glomerular filtration in the kidneys. If kidney function and glomerular filtration rate decline, the blood ...
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Similarly, calculated measurements of renal function (such as the Cockcroft-Gault formula) are unlikely to reflect actual activity of the kidney, as these calculations were developed for patients in whom the circulatory system correlates with the body weight; this relation is lost in a post-hemicorporectomy patient. [citation needed]
De'Vondre Campbell, a veteran linebacker in his first season with the 49ers, declined to play when his number was called in the third quarter