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An inverse relationship between dietary vitamin E and lung cancer was reported in observational studies, [72] but a large clinical trial in male tobacco smokers reported no impact on lung cancer between treatment and placebo, [73] and a trial which tracked people who chose to consume a vitamin E dietary supplement reported an increased risk of ...
Beta-carotene may also increase lung cancer. [157] [158] Overall, the large number of clinical trials carried out on antioxidant supplements suggest that either these products have no effect on health, or that they cause a small increase in mortality in elderly or vulnerable populations. [138] [159] [153]
Cancer prevention is the practice of taking active measures to decrease the incidence of cancer and mortality. [ 1 ] [ 2 ] The practice of prevention depends on both individual efforts to improve lifestyle and seek preventive screening , and socioeconomic or public policy related to cancer prevention. [ 3 ]
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For breast cancer, there is a replicated trend for women with a more "prudent or healthy" diet, i.e. higher in fruits and vegetables, to have a lower risk of cancer. [ 18 ] Unhealthy dietary patterns are associated with a higher body mass index suggesting a potential mediating effect of obesity on cancer risk.
Among the elderly, deficiencies in vitamins B12, B6, and folate are linked to cognitive decline and depressive symptoms. [ 173 ] The Recommended Dietary Allowance (RDA) for vitamin B12 is 0.9-2.4 μg/day, while the estimated average requirement in the U.S. and Canada is 0.7-2 μg/day.
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