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Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [2] [3] Most people are infected by the virus as children, when the disease produces few or no symptoms. [2] In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and ...
Kawasaki disease (also known as mucocutaneous lymph node syndrome) is a syndrome of unknown cause that results in a fever and mainly affects children under 5 years of age. [6] It is a form of vasculitis, in which medium-sized blood vessels become inflamed throughout the body. [1]
There are several forms of Epstein–Barr virus (EBV) infection. These include asymptomatic infections, the primary infection, infectious mononucleosis, and the progression of asymptomatic or primary infections to: 1) any one of various Epstein–Barr virus-associated lymphoproliferative diseases such as chronic active EBV infection, EBV+ hemophagocytic lymphohistiocytosis, Burkitt's lymphoma ...
It usually presents in children 4–7 years old and in almost all cases is associated with EBV infection. [31] Sporadic Burkitt lymphoma (sBL) is rare. It occurs in children and, less commonly, older (>60 years) adults. [16] It is found primarily in Northern and Eastern Europe, East Asia, and North America. [32] There are ~1,200 cases/year in ...
When infection occurs during adolescence or young adulthood, it causes infectious mononucleosis 35 to 50% of the time. [22] EBV infects B cells of the immune system and epithelial cells. Once EBV's initial lytic infection is brought under control, EBV latency persists in the individual's memory B cells for the rest of their life. [19] [23] [24]
The term childhood disease refers to disease that is contracted or becomes symptomatic before the age of 18 or 21 years old. Many of these diseases can also be contracted by adults. Some childhood diseases include:
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The under-five mortality rate (U5MR) is the number of deaths of infants and children under five years old per 1000 live births. The under-five mortality rate for the world is 39 deaths according to the World Bank and the World Health Organization (WHO). 5.3 million children under age five died in 2018, 14,722 every day. [1] [2] [3] The infant ...