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Benign paroxysmal positional vertigo (BPPV) is a disorder arising from a problem in the inner ear. [3] Symptoms are repeated, brief periods of vertigo with movement, characterized by a spinning sensation upon changes in the position of the head. [1]
Cochlear hydrops preferentially affects the apex of the cochlea where low-frequency sounds are interpreted. Due to the fluid imbalance in this area, parts of the cochlea are stretched or under more tension than usual, which can lead to distortions of sound, changes in pitch perception, or hearing loss, all usually in the low frequencies.
No cure for Ménière's disease is known, but medications, diet, physical therapy, counseling, and some surgical approaches can be used to manage it. [4] More than 85% of patients with Ménière's disease get better from changes in lifestyle, medical treatment, or minimally invasive surgical procedures.
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Endolymphatic hydrops may occur as a result of trauma such as a blow to the head, infection, degeneration of the inner ear, allergies, dehydration and loss of electrolytes or in extremely rare circumstances a benign tumor such as an endolymphatic sac tumor. [2]
Epley maneuver. The Epley maneuver or repositioning maneuver is a maneuver used by medical professionals to treat one common cause of vertigo, benign paroxysmal positional vertigo (BPPV) [1] [needs update] of the posterior or anterior canals of the ear. [2]
Betahistine, sold under the brand name Serc among others, is an anti-vertigo medication.It is commonly prescribed for balance disorders or to alleviate vertigo symptoms.It was first registered in Europe in 1970 for the treatment of Ménière's disease, but current evidence does not support its efficacy in treating it.
Ebselen has been entered into clinical trials as a lead compound intended for the potential treatment of various diseases. [2] Its most advanced clinical trial is a Phase III study in people with Meniere's disease, completed in July 2024. [3] In vitro, ebselen is a mimic of glutathione peroxidase and reacts with peroxynitrite. [4]
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