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The high blood pressure is gradual at early stages and may take at least 10–15 years to fully develop. Besides diabetes, other factors that may also increase high blood pressure include obesity, insulin resistance and high cholesterol levels. In general, fewer than 25 percent of diabetics have good control of their blood pressure.
A 2012 Cochrane review found that medications for mild hypertension did not reduce the risk of death, stroke, or cardiovascular disease, but did cause side effects in 1 of every 12 people. [ 8 ] [ 10 ] A second review that looked at higher-risk people (mostly diabetics whose blood pressure was difficult to control) found the medication ...
Hypertension is a very common condition, affecting about half of all adults in the U.S. But it doesn’t always have symptoms, so about one in three people don’t know they have it.
The first chemical for hypertension, sodium thiocyanate, was used in 1900 but had many side effects and was unpopular. [171] Several other agents were developed after the Second World War , the most popular and reasonably effective of which were tetramethylammonium chloride , hexamethonium , hydralazine , and reserpine (derived from the ...
Secondary hypertension (or, less commonly, inessential hypertension) is a type of hypertension which has a specific and identifiable underlying primary cause. It is much less common than essential hypertension , affecting only 5-10% of hypertensive patients.
[42] [43] Hydralazine and its derivatives are also used in the treatment of severe hypertension, although they should be avoided in emergencies. [43] They are no longer indicated as first-line therapy for high blood pressure due to side effects and safety concerns, but hydralazine remains a drug of choice in gestational hypertension. [42]