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Sertraline has been approved for major depressive disorder, obsessive–compulsive disorder (OCD), post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder, panic disorder, social anxiety disorder (SAD), and generalized anxiety disorder (GAD). Sertraline is approved for use in children with OCD. [21]
Sertraline is approved to treat a variety of conditions, including depression and anxiety, and, although no antidepressant works for everybody, experts generally agree that it’s one of the most ...
Cognitive-Behavioral Family Therapy for Anxious Children [18] Prevention: The prevention program based on Coping catis called EMOTION. It is designed for youth and their parents and targets both anxiety and depression. The program reduced the likelihood of children developing an anxiety disorder 6 months post-treatment. [19]
For children and adolescents, fluvoxamine is effective in treating a range of anxiety disorders. [ 42 ] [ 37 ] [ 43 ] Fluoxetine, sertraline, and paroxetine can also help with managing various forms of anxiety in children and adolescents.
"Raising Calm Kids in a World of Worry" by Ashley Graber and Maria Evans offers tools for parents to help ease their children's anxiety. - Penguin Random House.
Sertraline (Zoloft) As an SSRI antidepressant, escitalopram is commonly prescribed to treat depression. The FDA also approves it for the treatment of generalized anxiety disorder (GAD).
Paroxetine was the first drug to be approved for social anxiety disorder and it is considered effective for this disorder; sertraline and fluvoxamine were later approved for it as well. Escitalopram and citalopram are used off-label with acceptable efficacy, while fluoxetine is not considered to be effective for this disorder. [22]
Sertraline is the second most potent inhibitor of 5-HT re-uptake which has two very interesting characteristics that distinguish it i.e. sertraline's (1) inhibiting effect on DAT and NET and (2) the binding to sigma-1 (σ 1) receptor in CNS. [18]