Search results
Results From The WOW.Com Content Network
Cerebral blood flow (CBF) is the blood supply to the brain in a given period of time. [8] In an adult, CBF is typically 750 millilitres per minute or 15.8 ± 5.7% of the cardiac output. [9] This equates to an average perfusion of 50 to 54 millilitres of blood per 100 grams of brain tissue per minute. [10] [11] [12]
Chronic cerebrospinal venous insufficiency (CCSVI or CCVI) is a term invented by Italian researcher Paolo Zamboni in 2008 to describe compromised flow of blood in the veins draining the central nervous system. [1] [2] Zamboni hypothesized that it might play a role in the cause or development of multiple sclerosis (MS).
The pathophysiology of cranial venous outflow obstruction involves the disruption of normal venous drainage from the brain. Cerebral veins play a crucial role in draining brain interstitial fluid (ISF), and their significance has been linked in various neurological conditions. [1] It can be caused by extrinsic or intrinsic anomalies. [7]
Both biopsy samples and various types of brain scans have shown an increased water content of the brain tissue. It remains unclear why this might be the case. [5] The third theory suggests that restricted venous drainage from the brain may be impaired resulting in congestion. Many people with IIH have narrowing of the transverse sinuses. [15]
An increase in pressure, most commonly due to head injury leading to intracranial hematoma or cerebral edema, can crush brain tissue, shift brain structures, contribute to hydrocephalus, cause brain herniation, and restrict blood supply to the brain. [13] It is a cause of reflex bradycardia. [14]
An alternative definition of CPP is: [1] = where: MAP is mean arterial pressure ICP is intracranial pressure JVP is jugular venous pressure. This definition may be more appropriate if considering the circulatory system in the brain as a Starling resistor, where an external pressure (in this case, the intracranial pressure) causes decreased blood flow through the vessels.
In general, decrease in blood flow to the brain can be a result of thrombosis causing a partial or full blockage of blood vessels, hypotension in systemic circulation (and consequently the brain), or cardiac arrest. This decrease in blood flow in the cerebral vascular system can result in a buildup of metabolic wastes generated by neurons and ...
3D model of cerebral veins. In human anatomy, the cerebral veins are blood vessels in the cerebral circulation which drain blood from the cerebrum of the human brain.They are divisible into external (superficial cerebral veins) and internal (internal cerebral veins) groups according to the outer or inner parts of the hemispheres they drain into.