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  2. COVID-19 - Wikipedia

    en.wikipedia.org/wiki/COVID-19

    The storm causes acute respiratory distress syndrome, blood clotting events such as strokes, myocardial infarction, encephalitis, acute kidney injury, and vasculitis. The production of IL-1 , IL-2 , IL-6 , TNF-alpha , and interferon-gamma , all crucial components of normal immune responses, inadvertently become the causes of a cytokine storm.