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Quinine has diverse unwanted interactions with numerous prescription drugs, such as potentiating the anticoagulant effects of warfarin. [5] It is a strong inhibitor of CYP2D6, [38] an enzyme involved in the metabolism of many drugs.
People who rely on Qualaquin, also known as quinine sulfate, to combat their nighttime leg cramps are putting their lives at risk, warned the Food and Drug Administration. The federal agency ...
Quinidine is a class IA antiarrhythmic agent used to treat heart rhythm disturbances. [1] It is a diastereomer of antimalarial agent quinine, [2] originally derived from the bark of the cinchona tree.
As with other quinoline antimalarial drugs, the antimalarial mechanism of action of quinine has not been fully resolved. The most accepted model is based on hydrochloroquinine and involves the inhibition of hemozoin biocrystallization, which facilitates the aggregation of cytotoxic heme. Free cytotoxic heme accumulates in the parasites, causing ...
Tonic water is known to cause fixed eruptions, which is a type of skin reaction to drugs, [15] due to the quinine content. Various scientific journals have reported that repeated intake of tonic water can cause fixed eruptions with varying severity, with one reporting the onset of Stevens-Johnson syndrome . [ 16 ]
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