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It is a progestin that is also used in combination with ethinylestradiol, an estrogen, as a vaginal ring under the brand names NuvaRing and Circlet. [14] Etonogestrel is effective as a means of birth control and lasts at least three or four years with some data showing effectiveness for five years. [9] [11] Following removal, fertility quickly ...
Progestogens have been found to maximally suppress circulating testosterone levels in men by up to 70 to 80% at sufficiently high doses. [ 219 ] [ 220 ] This is notably less than that achieved by GnRH analogues , which can effectively abolish gonadal production of testosterone and suppress circulating testosterone levels by as much as 95%. [ 221 ]
A contraceptive implant is an implantable medical device used for the purpose of birth control.The implant may depend on the timed release of hormones to hinder ovulation or sperm development, the ability of copper to act as a natural spermicide within the uterus, or it may work using a non-hormonal, physical blocking mechanism.
lower estrogen exposure than with combined oral contraceptive pills or the contraceptive patch Ortho Evra. [12] [15] [16] a low incidence of estrogenic side effects such as nausea and breast tenderness [13] [17] a low incidence of irregular bleeding despite its lower estrogen dose [13] [17]
Suppression of estrogen receptors in the ventromedial nucleus of the hypothalamus in female rats has been observed to reduce female proceptivity and receptivity. [16] Proceptivity and receptivity in the female rat are indicators of sexual motivation, thus indicating a direct relationship between estrogen levels and sexual motivation.
High-dose estrogen therapy works by suppressing testosterone levels, similarly to high-dose progestogen therapy and gonadotropin-releasing hormone (GnRH) modulator therapy. [45] Lower dosages of estrogens have also been used in combination with high-dose progestogen therapy in the treatment of sexual deviance in men. [ 45 ]
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