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  2. In vitro - Wikipedia

    en.wikipedia.org/wiki/In_vitro

    A method which could help decrease animal testing is the use of in vitro batteries, where several in vitro assays are compiled to cover multiple endpoints. Within developmental neurotoxicity and reproductive toxicity there are hopes for test batteries to become easy screening methods for prioritization for which chemicals to be risk assessed ...

  3. In vitro toxicology - Wikipedia

    en.wikipedia.org/wiki/In_vitro_toxicology

    In vitro toxicity testing is the scientific analysis of the toxic effects of chemical substances on cultured bacteria or mammalian cells. [1] In vitro (literally 'in glass') testing methods are employed primarily to identify potentially hazardous chemicals and/or to confirm the lack of certain toxic properties in the early stages of the development of potentially useful new substances such as ...

  4. WHO model list of essential in vitro diagnostics - Wikipedia

    en.wikipedia.org/wiki/WHO_Model_List_of...

    Where there is a health care facility with laboratories, tests are divided into either general tests or disease-specific tests for clinical laboratories, and disease-specific tests for blood screening laboratories. [5] For each group of tests, the EDL specifies the test's name, purpose, assay format and type of specimen. [6]

  5. Laboratory developed test - Wikipedia

    en.wikipedia.org/wiki/Laboratory_developed_test

    Laboratory-developed tests (LDTs) are a class of in vitro diagnostics (IVDs) designed, manufactured, and used within a single laboratory. They are employed for various medical diagnoses and research applications, offering advantages in flexibility and fostering innovation in the diagnostics field.

  6. In vitro muscle testing - Wikipedia

    en.wikipedia.org/wiki/In_vitro_muscle_testing

    In vitro testing allows for exact stimulation of the muscle, providing precise data on innate tissue behavior. [4] Isolated muscle testing limits other factors on the environment around the tissue such as substrates. In vitro isolated muscle testing is a beneficial procedure based on its ideal accuracy, precision, and reproducibly. [5]

  7. Radioimmunoassay - Wikipedia

    en.wikipedia.org/wiki/Radioimmunoassay

    A radioimmunoassay (RIA) is an immunoassay that uses radiolabeled molecules in a stepwise formation of immune complexes.A RIA is a very sensitive in vitro assay technique used to measure concentrations of substances, usually measuring antigen concentrations (for example, hormone levels in blood) by use of antibodies.

  8. Toxicology testing - Wikipedia

    en.wikipedia.org/wiki/Toxicology_testing

    Toxicology testing is commonly conducted during preclinical development for a substance intended for human exposure. Stages of in silico, in vitro and in vivo research are conducted to determine safe exposure doses in model organisms. If necessary, the next phase of research involves human toxicology testing during a first-in-man study.

  9. Dissolution testing - Wikipedia

    en.wikipedia.org/wiki/Dissolution_testing

    In the pharmaceutical industry, drug dissolution testing is routinely used to provide critical in vitro drug release information for both quality control purposes, i.e., to assess batch-to-batch consistency of solid oral dosage forms such as tablets, and drug development, i.e., to predict in vivo drug release profiles. [1]