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Chelation therapy is the preferred medical treatment for metal poisoning, [1] [7] including acute mercury, iron (including in cases of sickle-cell disease and thalassemia), [8] [9] arsenic, lead, uranium, plutonium and other forms of toxic metal poisoning.
CHELATION THERAPY HAS been around for decades as a treatment for toxic metal poisoning. But, there have also been claims that the therapy could help several other conditions.
Dimercaprol has long been the mainstay of chelation therapy for lead or arsenic poisoning, [7] and it is an essential drug. [6] It is also used as an antidote to the chemical weapon Lewisite. Nonetheless, because it can have serious adverse effects, researchers have also pursued development of less toxic analogues, [7] such as succimer.
Succimer, sold under the brand name Chemet among others, is a medication used to treat lead, mercury, and arsenic poisoning. [4] When radiolabeled with technetium-99m, it is used in many types of diagnostic testing. [5]
An option for treatment of metal poisoning may be chelation therapy, a technique involving the administration of chelation agents to remove metals from the body. Toxic metals sometimes imitate the action of an essential element, interfering with the metabolic processes resulting in illness .
In Wilson's disease, a rare genetic disorder of copper metabolism, penicillamine treatment relies on its binding to accumulated copper and elimination through urine. [4] Penicillamine was the second line treatment for arsenic poisoning, after dimercaprol (BAL). [5] It is no longer recommended. [6]
According to WHO, short-term signs of arsenic poisoning include: Vomiting. Diarrhea. Stomach pain. Muscle cramping. Exposure to elevated levels of inorganic arsenic can be particularly dangerous ...
Heavy metal detox, or detoxification, is the removal of toxic heavy metal substances from the body. In conventional medicine, detoxification can also be achieved artificially by techniques such as dialysis and (in a very limited number of cases) chelation therapy.