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The volume of body fluid, blood glucose, oxygen, and carbon dioxide levels are also tightly homeostatically maintained. The volume of extracellular fluid in a young adult male of 70 kg (154 lbs) is 20% of body weight – about fourteen liters. Eleven liters are interstitial fluid and the remaining three liters are plasma. [7]
The extracellular fluid compartment is further subdivided into the interstitial fluid and the intravascular fluid compartments. Body fluids, bodily fluids, or biofluids, sometimes body liquids, are liquids within the body of an organism. [1] In lean healthy adult men, the total body water is about 60% (60–67%) of the total body weight; it is ...
Extracellular fluid (1/3 of body water) is fluid contained in areas outside of cells. For a 40-litre body, about 15 litres is extracellular, [9] which amounts to 37.5%. Plasma (1/5 of extracellular fluid). Of this 15 litres of extracellular fluid, plasma volume averages 3 litres, [9] or 20%. Interstitial fluid (4/5 of extracellular fluid)
The transcellular fluid is the portion of total body fluid that is formed by the secretory activity of epithelial cells and is contained within specialized epithelial-lined compartments. Fluid does not normally collect in larger amounts in these spaces, [6] [7] and any significant fluid collection in these spaces is physiologically ...
The total amount of water in the body needs to be kept in balance. Fluid balance involves keeping the fluid volume stabilized, and also keeping the levels of electrolytes in the extracellular fluid stable. Fluid balance is maintained by the process of osmoregulation and by behavior.
The majority of fluid output occurs via the urine, approximately 1500 ml/day (approx 1.59 qt/day) in the normal adult resting state. [12] [13] Some fluid is lost through perspiration (part of the body's temperature control mechanism) and as water vapor in exhaled air. These are termed "insensible fluid losses" as they cannot be easily measured.
The osmoreceptors have a defined functionality as neurons that are endowed with the ability to detect extracellular fluid osmolarity. Osmoreceptors have aquaporin 4 proteins spanning through their plasma membranes in which water can diffuse, from an area of high to low water concentration. If plasma osmolarity rises above 290 mOsmol/L, then ...
Sodium is the most prominent cation in extracellular fluid: in the 15 L of extracellular fluid in a 70 kg human there is around 50 grams of sodium, 90% of the body's total sodium content. Some potent neurotoxins , such as batrachotoxin , increase the sodium ion permeability of the cell membranes in nerves and muscles, causing a massive and ...