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Extracellular fluid makes up about one-third of body fluid, the remaining two-thirds is intracellular fluid within cells. [3] The main component of the extracellular fluid is the interstitial fluid that surrounds cells.
The main intravascular fluid in mammals is blood, a complex mixture with elements of a suspension (blood cells), colloid (), and solutes (glucose and ions).The blood represents both the intracellular compartment (the fluid inside the blood cells) and the extracellular compartment (the blood plasma).
The total body of water is divided into fluid compartments, [1] between the intracellular fluid compartment (also called space, or volume) and the extracellular fluid (ECF) compartment (space, volume) in a two-to-one ratio: 28 (28–32) liters are inside cells and 14 (14–15) liters are outside cells.
Jackson's texts states 70% of body fluid is intracellular. [10] Extracellular fluid (1/3 of body water) is fluid contained in areas outside of cells. For a 40-litre body, about 15 litres is extracellular, [9] which amounts to 37.5%. Plasma (1/5 of extracellular fluid). Of this 15 litres of extracellular fluid, plasma volume averages 3 litres ...
This space is usually taken to be outside the plasma membranes, and occupied by fluid (see extracellular matrix). The term is used in contrast to intracellular (inside the cell). According to the Gene Ontology , the extracellular space is a cellular component defined as: "That part of a multicellular organism outside the cells proper, usually ...
The pH of the intracellular fluid is 7.4. [ 16 ] while mouse cell cytosolic pH ranges between 7.0 and 7.4, and is usually higher if a cell is growing. [ 17 ] The viscosity of cytoplasm is roughly the same as pure water, although diffusion of small molecules through this liquid is about fourfold slower than in pure water, due mostly to ...
Volume contraction of extracellular fluid is directly coupled to and almost proportional to volume contraction of blood plasma, which is termed hypovolemia. [2] [3] Thus, it primarily affects the circulatory system, potentially causing hypovolemic shock.
The total body water can be divided into two compartments called extracellular fluid (ECF) and intracellular fluid (ICF). The majority of the sodium in the body stays in the extracellular fluid compartment. [27] This compartment consists of the fluid surrounding the cells and the fluid inside the blood vessels.