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Waking up earlier in the morning increases the response. [11]Shift work: nurses working on morning shifts with very early awakening (between 4:00–5:30 a.m.) had a greater and prolonged cortisol awakening response than those on the late day shift (between 6:00–9:00 a.m.) or the night shift (between 11:00 a.m.–2:00 p.m.). [12]
Dexamethasone is a fluorinated glucocorticoid medication [10] used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive pulmonary disease (COPD), croup, brain swelling, eye pain following eye surgery, superior vena cava syndrome (a complication of some forms of cancer), [11] and along with antibiotics in tuberculosis. [10]
Amphetamine (methamphetamine having been used historically, such as during the Second World War), which is a strong psychostimulant drug; no longer approved officially for use by the U.S. Air Force, [2] possibly due to safety concerns brought up in the wake of incidents like the Tarnak Farm incident.
Dexamethasone is an exogenous steroid that provides negative feedback to the pituitary gland to suppress the secretion of adrenocorticotropic hormone (ACTH). Specifically, dexamethasone binds to glucocorticoid receptors in the anterior pituitary gland, which lie outside the blood–brain barrier , resulting in regulatory modulation.
"How Do You Sleep?" is a song by English singer Sam Smith, released on 19 July 2019. [4] Smith co-wrote the song with Savan Kotecha , Max Martin and Ilya , the latter of whom produced the song. [ 2 ] [ 5 ] The song appears on Smith's third studio album Love Goes (2020).
"Up at Night" is a song by American singer Kehlani, featuring vocals from Canadian singer Justin Bieber. It was released through Atlantic Records as the third single from Kehlani's third album, Blue Water Road , on March 30, 2022.
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Consuming caffeine to stay awake at night may lead to sleeplessness, anxiety, frequent nighttime awakenings, and overall poorer sleep quality. [139] The main metabolite of melatonin (6-sulfatoxymelatonin) gets reduced with consumption of caffeine in the day, which is one of the mechanisms by which sleep is interrupted.