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  2. Colchicine - Wikipedia

    en.wikipedia.org/wiki/Colchicine

    Colchicine has a narrow therapeutic index, so overdosing is a significant risk. Common side effects of colchicine include gastrointestinal upset, particularly at high doses. [14] Severe side effects may include pancytopenia (low blood cell counts) and rhabdomyolysis (damage to skeletal muscle), and the medication can be deadly in overdose. [11]

  3. Cyclooxygenase-2 inhibitor - Wikipedia

    en.wikipedia.org/wiki/Cyclooxygenase-2_inhibitor

    The VIGOR trial results were published in 2000 in the New England Journal of Medicine [47] Bombardier and her research team claimed that there was "an increase in myocardial infarction in the patients given rofecoxib (0.4%) compared with those given naproxen (0.1%)" and "patients given naproxen experienced 121 side effects compared with 56 in ...

  4. Naproxen - Wikipedia

    en.wikipedia.org/wiki/Naproxen

    Naproxen should be taken orally with, or just after food, to decrease the risk of gastrointestinal side effects. [24] Persons with a history of ulcers or inflammatory bowel disease should consult a doctor before taking naproxen. [24] In U.S. markets, naproxen is sold with boxed warnings about the risk of gastrointestinal ulceration or bleeding. [1]

  5. Oxycodone/naloxone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone/naloxone

    Oxycodone/naloxone, sold under the brand name Targin among others, is a combination pain medication available as modified-release tablets administered by mouth. [5]The oxycodone component is an opioid and is responsible for the pain-relieving effects.

  6. Naproxcinod - Wikipedia

    en.wikipedia.org/wiki/Naproxcinod

    It is a derivative of naproxen with a nitroxybutyl ester to allow it to also act as a nitric oxide (NO) donor. This second mechanism of action makes naproxcinod the first in a new class of drugs, the cyclooxygenase inhibiting nitric oxide donators (CINODs), that are hoped to produce similar analgesic efficacy to traditional NSAIDs, but with ...

  7. 7 Uses for Prune Juice for Constipation, According to ...

    www.aol.com/7-uses-prune-juice-constipation...

    Our nutritionists share how long it takes prune juice to work for constipation and how much to drink. Studies say yes. 7 Uses for Prune Juice for Constipation, According to Registered Dietitians

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