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Benzocaine, sold under the brand name Orajel amongst others, is a local anesthetic, belonging to the amino ester drug class, commonly used as a topical painkiller or in cough drops. It is the active ingredient in many over-the-counter anesthetic ointments such as products for oral ulcers. It is combined with antipyrine to form A/B ear drops.
Pain and discomfort can be the result of minor burns to the eye’s surface, a condition called solar keratitis, Dr. Daniel Lattin, an ophthalmologist at Nemours Children’s Health in ...
Together with the collaboration a chemistry professor, Kern created and developed Orajel to relieve toothaches. [1] The over-the-counter gel was later used to alleviate mouth sores as well. [1] In 1961, Kern sold the Orajel and the rest of his company to Del Laboratories. [1] He retired the pharmaceutical industry when he was 62 years old. [1]
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Long-term contact lens use can lead to alterations in corneal thickness, stromal thickness, curvature, corneal sensitivity, cell density, and epithelial oxygen uptake. . Other structural changes may include the formation of epithelial vacuoles and microcysts (containing cellular debris), corneal neovascularization, as well as the emergence of polymegethism in the corneal endoth
The interior of the eye lacks lymph vessels but is highly vascularized, and many immune cells reside in the uvea, including mostly macrophages, dendritic cells, and mast cells. [1] These cells fight off intraocular infections, and intraocular inflammation can manifest as uveitis (including iritis ) or retinitis .
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With the eye generally profusely watering, the type of tears being produced have little adhesive property. Water or saline eye drops tend therefore to be ineffective. Rather a 'better quality' of tear is required with higher 'wetting ability' (i.e. greater amount of glycoproteins) and so artificial tears (e.g. viscotears) are applied frequently.