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  2. He Jiankui affair - Wikipedia

    en.wikipedia.org/wiki/He_Jiankui_affair

    t. e. The He Jiankui affair is a scientific and bioethical controversy concerning the use of genome editing following its first use on humans by Chinese scientist He Jiankui, who edited the genomes of human embryos in 2018. [1][2] He became widely known on 26 November 2018 [3] after he announced that he had created the first human genetically ...

  3. Jennifer Doudna - Wikipedia

    en.wikipedia.org/wiki/Jennifer_Doudna

    Jennifer Doudna. Jennifer Anne Doudna ForMemRS (/ ˈdaʊdnə /; [1] born February 19, 1964) [2] is an American biochemist who has pioneered work in CRISPR gene editing, and made other fundamental contributions in biochemistry and genetics. She received the 2020 Nobel Prize in Chemistry, with Emmanuelle Charpentier, "for the development of a ...

  4. The Code Breaker - Wikipedia

    en.wikipedia.org/wiki/The_Code_Breaker

    The Code Breaker: Jennifer Doudna, Gene Editing, and the Future of the Human Race is a non-fiction book authored by American historian and journalist Walter Isaacson. Published in March 2021 by Simon & Schuster , it is a biography of Jennifer Doudna , the winner of the 2020 Nobel Prize in Chemistry for her work on the CRISPR system of gene ...

  5. Human germline engineering - Wikipedia

    en.wikipedia.org/wiki/Human_germline_engineering

    Human germline engineering could be used to heritably cure genetic disorders and other diseases, and to give specific traits to human babies. For example, The Berlin Patient has a genetic mutation in the CCR5 gene (which codes for a protein on the surface of white blood cells, targeted by the HIV virus) that deactivates the expression of CCR5, conferring innate resistance to HIV.

  6. CRISPR - Wikipedia

    en.wikipedia.org/wiki/CRISPR

    CRISPR gene editing is a revolutionary technology that allows for precise, targeted modifications to the DNA of living organisms. Developed from a natural defense mechanism found in bacteria, CRISPR-Cas9 is the most commonly used system, that allows "cutting" of DNA at specific locations and either delete, modify, or insert genetic material.

  7. Jo Zayner - Wikipedia

    en.wikipedia.org/wiki/Jo_Zayner

    February 8, 1981 (age 43) Nationality. American. Occupation (s) Bio-engineer, biohacker, and CEO of The ODIN. Known for. Self-experimentation with genetic material. Jo Zayner (formerly Josiah Zayner; alternatively Josie; born February 8, 1981) is a biohacker, artist, and scientist best known for their self-experimentation and work making hands ...

  8. He Jiankui - Wikipedia

    en.wikipedia.org/wiki/He_Jiankui

    His story is narrated in the 2020 book The Mutant Project: Inside the Global Race to Genetically Modify Humans, written by Eben Kirksey, an anthropologist at the University of Oxford. [106] [107] A documentary book CRISPR People: The Science and Ethics of Editing Humans, written by Henry Greely, was published in 2021. [108] [109]

  9. CRISPR interference - Wikipedia

    en.wikipedia.org/wiki/CRISPR_interference

    CRISPR interference (CRISPRi) is a genetic perturbation technique that allows for sequence-specific repression of gene expression in prokaryotic and eukaryotic cells. [1] It was first developed by Stanley Qi and colleagues in the laboratories of Wendell Lim , Adam Arkin, Jonathan Weissman , and Jennifer Doudna . [ 2 ]