Ads
related to: atropine eye drops indications
Search results
Results From The WOW.Com Content Network
Topical atropine is used as a cycloplegic, to temporarily paralyze the accommodation reflex, and as a mydriatic, to dilate the pupils. [15] Atropine degrades slowly, typically wearing off in 7 to 14 days, so it is generally used as a therapeutic mydriatic, whereas tropicamide (a shorter-acting cholinergic antagonist) or phenylephrine (an α-adrenergic agonist) is preferred as an aid to ...
Atropine has less sting effect, but can be toxic or fatal if ingested in large quantities by children or adults. With eye drops, systemic effects are minimal to nonexistent due to very low absorption into the bloodstream. [9]
Cycloplegic drugs are generally muscarinic receptor antagonists such as atropine, cyclopentolate, homatropine, scopolamine and tropicamide.
Cyclopentolate was first synthesized in 1952 as a chemical analogue of atropine. It was one of several derivatives of an analogue to tropic acid which were tested for pharmacological action "in a search for new and better antispasmodic agents." [15] Brand names for cyclopentolate include Cyclogyl, Cylate, Mydrilate, and Pentolair. [16]
It is used in eye drops as a cycloplegic (to temporarily paralyze accommodation), and as a mydriatic (to dilate the pupil). The related chemical compound homatropine methylbromide (methylhomatropine) is a different medication. Homatropine is less potent than atropine and has a shorter duration of action.
Hyoscyamine (also known as daturine or duboisine) is a naturally occurring tropane alkaloid and plant toxin. It is a secondary metabolite found in certain plants of the family Solanaceae, including henbane, mandrake, angel's trumpets, jimsonweed, the sorcerers' tree, and Atropa belladonna (deadly nightshade).