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In traumatic brain injury (TBI), primary brain injury occurs during the initial insult, and results from displacement of the physical structures of the brain. [1] Secondary brain injury occurs gradually and may involve an array of cellular processes. [1] [2] Secondary injury, which is not caused by mechanical damage, can result from the primary ...
More than 50% of patients who suffer from a traumatic brain injury will develop psychiatric disturbances. [6] Although precise rates of anxiety after brain injury are unknown, a 30-year follow-up study of 60 patients found 8.3% of patients developed a panic disorder, 1.7% developed an anxiety disorder, and 8.3% developed a specific phobia. [7]
Closed head injury (coup contrecoup) can damage more than the impact sites on the brain, as axon bundles may be torn or twisted, blood vessels may rupture, and elevated intracranial pressure can distort the walls of the ventricles. [7] [10] [11] Diffuse axonal injury is a key pathology in concussive brain injury. [5] The visual system may be ...
[12] [13] All traumatic brain injuries are head injuries, but the latter term may also refer to injury to other parts of the head; [14] [15] [16] however, the terms head injury and brain injury are often used interchangeably. [17] Similarly, brain injuries fall under the classification of central nervous system injuries [18] and neurotrauma. [19]
Glasgow Coma Scale (GCS) is the most widely used scoring system used to assess the level of severity of a brain injury. This method is based on the objective observations of specific traits to determine the severity of a brain injury. It is based on three traits: eye opening, verbal response, and motor response, gauged as described below. [35]
Diffuse injury has more microscopic injury than macroscopic injury and is difficult to detect with CT and MRI, but its presence can be inferred when small bleeds are visible in the corpus callosum or the cerebral cortex. [34] MRI is more useful than CT for detecting characteristics of diffuse axonal injury in the subacute and chronic time ...
Wallerian degeneration is named after Augustus Volney Waller.Waller experimented on frogs in 1850, by severing their glossopharyngeal and hypoglossal nerves. He then observed the distal nerves from the site of injury, which were separated from their cell bodies in the brain stem. [5]
A cerebral laceration is a type of traumatic brain injury that occurs when the tissue of the brain is mechanically cut or torn. [1] The injury is similar to a cerebral contusion; however, according to their respective definitions, the pia-arachnoid membranes are torn over the site of injury in laceration and are not torn in contusion.