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The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
.66 In full remission.65 In partial remission.61 Mild.62 Moderate.63 Severe without psychotic features.64 Severe with psychotic features.60 Unspecified.7 Bipolar I disorder, most recent episode unspecified.0x Bipolar I disorder, single manic episode .06 In full remission.05 In partial remission.01 Mild.02 Moderate
In physiology and medicine, depression [1] refers to a lowering, in particular a reduction in a specific biological variable or the functions of an organ. It is the opposite of elevation. For example, it is possible to refer to "depressed thyroid function" or to a depression of blood flow in a particular area. Further examples:
Atypical depression is four times more common in females than in males. [7] Individuals with features of atypical depression tend to report an earlier age of onset (e.g., while in high school) of their depressive episodes. These episodes tend to be more chronic than those of major depressive disorder [2] and only have partial remission between ...
A remission may be considered a partial remission or a complete remission. Each disease, type of disorder , or clinical trial can have its own definition of a partial remission. For example, a partial remission for cancer may be defined as a 50% or greater reduction in the measurable parameters of tumor growth as may be found on physical ...
The STAR*D trial included remission (the near-absence of symptoms, rather than simply a reduction in symptoms) as an outcome measure, as there is evidence that patients with depression who achieve remission function better and are less prone to relapse than those who achieve only partial improvement in symptoms [1]
These have shown promise in treating refractory depression but come with serious side effects. [25] Among studies studies meeting the Cochrane 2019 inclusion criteria, two report that quetiapine augmentation does not improve overall quality of life. [17] One study on the 5-HT 1A receptor partial agonist buspirone met the Cochrane 2019 inclusion ...