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  2. Citicoline - Wikipedia

    en.wikipedia.org/wiki/Citicoline

    Citicoline may have neuroprotective effects due to its preservation of cardiolipin and sphingomyelin, preservation of arachidonic acid content of phosphatidylcholine and phosphatidylethanolamine, partial restoration of phosphatidylcholine levels, and stimulation of glutathione synthesis and glutathione reductase activity.

  3. Neurobiological effects of physical exercise - Wikipedia

    en.wikipedia.org/wiki/Neurobiological_effects_of...

    Neuroplasticity is the process by which neurons adapt to a disturbance over time, and most often occurs in response to repeated exposure to stimuli. [27] Aerobic exercise increases the production of neurotrophic factors [note 1] (e.g., BDNF, IGF-1, VEGF) which mediate improvements in cognitive functions and various forms of memory by promoting blood vessel formation in the brain, adult ...

  4. Glycerophosphorylcholine - Wikipedia

    en.wikipedia.org/wiki/Glycerophosphorylcholine

    It is also a parasympathomimetic acetylcholine precursor [1] which has been investigated for its potential for the treatment of Alzheimer's disease [2] and other dementias. [3] Alpha-GPC rapidly delivers choline to the brain across the blood–brain barrier and is a biosynthetic precursor of acetylcholine. [2] It is a non-prescription drug in ...

  5. Neuropathy target esterase - Wikipedia

    en.wikipedia.org/wiki/Neuropathy_target_esterase

    Neuropathy target esterase is a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal ...

  6. 1-Lysophosphatidylcholine - Wikipedia

    en.wikipedia.org/wiki/1-Lysophosphatidylcholine

    Enzymes having phospholipase B activity hydrolyze both the sn-1 and sn-2 positions, so they produce both 1-lysoPC and 2-lysoPC. In humans, a number of enzymes with phospholipase A1 exist: they include two from the brain (with different optimal pHs), two from the liver (one cytosomal and one membrane-bound) [4] and one from the mitochondrion. [5]

  7. Phosphatidylcholine - Wikipedia

    en.wikipedia.org/wiki/Phosphatidylcholine

    1-Oleoyl-2-palmitoyl-phosphatidylcholine. Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup.They are a major component of biological membranes and can easily be obtained from a variety of readily available sources, such as egg yolk or soybeans, from which they are mechanically or chemically extracted using hexane.

  8. Lysophosphatidylcholine - Wikipedia

    en.wikipedia.org/wiki/Lysophosphatidylcholine

    Lysophosphatidylcholines are produced within cells mainly by the enzyme phospholipase A2, which removes one of the fatty acid groups from phosphatidylcholine to produce LPC. [2] Among other properties, they activate endothelial cells during early atherosclerosis .

  9. Haemodynamic response - Wikipedia

    en.wikipedia.org/wiki/Haemodynamic_response

    Changes in brain activity are closely coupled with changes in blood flow in those areas, and knowing this has proved useful in mapping brain functions in humans. The measurement of haemodynamic response, in a clinical setting, can be used to create images of the brain in which especially active and inactive regions are shown as distinct from ...

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    citicoline and phosphatidylcholineglycerophosphoryl choline precursor