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Perilymph and endolymph have unique ionic compositions suited to their functions in regulating electrochemical impulses of hair cells necessary for hearing. The electric potential of endolymph is ~80-90 mV more positive than perilymph due to a higher concentration of potassium cations (K +) in endolymph and higher sodium (Na +) in perilymph. [4]
Endolymph has a high positive potential (80–120 mV in the cochlea), relative to other nearby fluids such as perilymph, due to its high concentration of positively charged ions. It is mainly this electrical potential difference that allows potassium ions to flow into the hair cells during mechanical stimulation of the hair bundle.
The organ of Corti, the sensory epithelium, a cellular layer on the basilar membrane, in which sensory hair cells are powered by the potential difference between the perilymph and the endolymph; Hair cells, sensory cells in the organ of Corti, topped with hair-like structures called stereocilia
With the movement of the basilar membrane, a shear force is created and a small potential is generated due to a difference in potential between the endolymph (scala media, +80 mV) and the perilymph (vestibular and tympanic ducts, 0 mV). EP is highest in the basal turn of the cochlea (95 mV in mice) and decreases in the magnitude towards the ...
These are located within the bony labyrinth, which is filled with fluid called perilymph, similar in composition to cerebrospinal fluid. The chemical difference between the fluids endolymph and perilymph fluids is important for the function of the inner ear due to electrical potential differences between potassium and calcium ions. [citation ...
The endolymph is the fluid that surrounds the apical surfaces of hair cells. Potassium is the major cation in the endolymph and is thought to be responsible for carrying the receptor currents in the cochlea. Perilymph is found surrounding the sides and the bases of the hair cells. Perilymph is low in potassium and high in sodium.
The footplate of the stapes connects to the oval window, the beginning of the inner ear. When the stapes presses on the oval window, it causes the perilymph, the liquid of the inner ear to move. The middle ear thus serves to convert the energy from sound pressure waves to a force upon the perilymph of the inner ear.
It helps to transmit vibrations from fluid in the vestibular duct to the cochlear duct. Together with the basilar membrane, it creates a compartment in the cochlea filled with endolymph, which is important for the function of the spiral organ of Corti. It allows nutrients to travel from the perilymph to the endolymph of the membranous labyrinth.