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Initially, the GeneCards database had two main features: delivery of integrated biomedical information for a gene in ‘card’ format, and a text-based search engine. Since 1998, the database has integrated more data resources and data types, such as protein expression and gene network information.
The TMEM229B gene is located on the sense strand (-) of chromosome 14 at location 14q24.1 and spans the chromosomal locus 67,936,983—67,982,021. [8] Covering a total of 45,038 base pairs (bp) along the chromosome, the TMEM229B gene has a total of 3 exons in its primary unspliced transcript mRNA of 4,068 bp.
Human protein-coding gene pages: •Python code for maintaining the list •List of human protein-coding genes page 1 covers genes A1BG–EPGN •List of human protein-coding genes page 2 covers genes EPHA1–MTMR3 •List of human protein-coding genes page 3 covers genes MTMR4–SLC17A7
Unusual names have caused issues for scientists explaining genetic diseases to lay-people, such as when an individual is affected by a gene with an offensive or insensitive name. [13] This has particularly been noted in patients with a defect in the sonic hedgehog gene pathway and the disease formerly named CATCH22 for "cardiac anomaly, T-cell ...
The gene is associated with multiple red blood cell phenotypes in African Americans – though the exact function or effect of the gene was not entirely clear. [12] Review of GeneCards’ current database on the FAM234A gene provided no additional elucidation on the function of the gene. [10]
The DisGeNET database integrates over 400 000 associations between > 17 000 genes and > 14 000 diseases from human to animal model expert curated databases with text mined GDAs from MEDLINE using a NLP-based approach. [4] The highlights of DisGeNET are the data integration, standardisation and a fine-grained tracking of the provenance information.
No interactions were found in the GeneCards database [9] or in the MINT database. [22] A STRING search resulted in two gene outputs. [ 23 ] These two gene interactions, though, are both in the evidence category of gene neighborhood, which does not necessarily suggest that these genes are interacting in any meaningful way, or are even expressed ...
LRRC40 is located on the negative DNA strand (see Sense (molecular biology)) of chromosome 1 from 70,611,483- 70,671,223. [24] The gene produces a 2958 base pair mRNA.There are 15 predicted exons in the human gene [9] with four other splice patterns predicted on GeneCards by the Alternative Splice Database.