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Initially, the GeneCards database had two main features: delivery of integrated biomedical information for a gene in ‘card’ format, and a text-based search engine. Since 1998, the database has integrated more data resources and data types, such as protein expression and gene network information.
The DisGeNET database integrates over 400 000 associations between > 17 000 genes and > 14 000 diseases from human to animal model expert curated databases with text mined GDAs from MEDLINE using a NLP-based approach. [4] The highlights of DisGeNET are the data integration, standardisation and a fine-grained tracking of the provenance information.
Human protein-coding gene pages: •Python code for maintaining the list •List of human protein-coding genes page 1 covers genes A1BG–EPGN •List of human protein-coding genes page 2 covers genes EPHA1–MTMR3 •List of human protein-coding genes page 3 covers genes MTMR4–SLC17A7
Unusual names have caused issues for scientists explaining genetic diseases to lay-people, such as when an individual is affected by a gene with an offensive or insensitive name. [14] This has particularly been noted in patients with a defect in the sonic hedgehog gene pathway and the disease formerly named CATCH22 for "cardiac anomaly, T-cell ...
The gene is associated with multiple red blood cell phenotypes in African Americans – though the exact function or effect of the gene was not entirely clear. [12] Review of GeneCards’ current database on the FAM234A gene provided no additional elucidation on the function of the gene. [10]
No interactions were found in the GeneCards database [9] or in the MINT database. [22] A STRING search resulted in two gene outputs. [ 23 ] These two gene interactions, though, are both in the evidence category of gene neighborhood, which does not necessarily suggest that these genes are interacting in any meaningful way, or are even expressed ...
The GDB Human Genome Database was a community curated collection of human genomic data. It was a key database in the Human Genome Project [ 1 ] [ 2 ] and was in service from 1989 to 2008. History
Chitinase domain-containing protein 1 (CHID1) is a highly conserved protein of unknown function located on the short (p) arm of chromosome 11 near the telomere. [5] The protein has 27 introns, which allows for many isoforms of this gene.