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Mitral regurgitation, also known as mitral insufficiency or mitral incompetence, is the backward flow of blood from the left ventricle, through the mitral valve, and into the left atrium, when the left ventricle contracts, resulting in a systolic murmur radiating to the left armpit. [5] [3]
Mitral valve prolapse is frequently associated with mild mitral regurgitation, [15] where blood aberrantly flows from the left ventricle into the left atrium during systole. In the United States , MVP is the most common cause of severe, non-ischemic mitral regurgitation. [ 4 ]
Mitral regurgitation: the backflow of blood from the left ventricle into the left atrium, owing to insufficiency of the mitral valve; it may be acute or chronic, and is usually due to mitral valve prolapse, rheumatic heart disease, or a complication of cardiac dilatation. See also Mitral regurgitation.
Mitral stenosis is almost always caused by rheumatic heart disease. [16] Less than 10% of aortic stenosis is caused by rheumatic heart disease. [15] [16] Rheumatic fever can also cause chronic mitral and aortic regurgitation. [16]
During open heart surgery for another issue (e.g. mitral valve), fixing the tricuspid valve may be considered, but medical consensus is unclear. Some argue that even mild to moderate tricuspid regurgitation should be addressed, while others take a more conservative approach. Infective endocarditis or traumatic lesions are other indications. [14]
Mitral valve prolapse: This is the most common cause of late systolic murmurs. It can be heard best over the apex of the heart, usually preceded by clicks. The most common cause of mitral valve prolapse is "floppy" valve (Barlow's) syndrome. If the prolapse becomes severe enough, mitral regurgitation may occur.
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