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Papillae vs pseudopapillae: True papillae are outgrowths of epithelium, surrounding fibrovascular cores of stroma and at least one blood vessel. In contrast, pseudopapillae (such as in solid pseudopapillary tumours) are nests of proliferating cells that eventually grow to become almost back-to-back, with cells in the centers of nests disintegrating, leaving rims of cells lining the periphery ...
Call–Exner bodies marked with black circles in an intermediate-high magnification micrograph of a granulosa cell tumour, a type of sex cord stromal tumour. H&E stain. H&E stain. Call–Exner bodies , giving a follicle-like appearance, are small eosinophilic fluid-filled punched out spaces between granulosa cells . [ 1 ]
Histopathologic types of kidney tumor, with relative incidences and prognoses. Cystic nephroma is seen at bottom right in pie chart. cystic partially differentiated nephroblastoma; cystic standard nephroblastoma (cystic Wilm's tumor) cystic mesoblastic nephroma; cystic renal cell carcinoma; other renal cysts
Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of the gastrointestinal tract. GISTs arise in the smooth muscle pacemaker interstitial cell of Cajal, or similar cells. [2] They are defined as tumors whose behavior is driven by mutations in the KIT gene (85%), [2] PDGFRA gene (10%), [2] or BRAF kinase (rare).
Sex cord/gonadal stromal tumor, NOS; Testicular/ovarian stromal tumor; M8591/1 Sex cord-gonadal stromal tumor, incompletely differentiated M8592/1 Sex cord-gonadal stromal tumor, mixed forms M8593/1 Stromal tumor with minor sex cord elements M8600/0 Thecoma, NOS Theca cell tumor; M8600/3 Thecoma, malignant M8601/0 Thecoma, luteinized M8602/0 ...
Granulosa cell tumours are tumours that arise from granulosa cells.They are estrogen-secreting tumours and present as large, complex, ovarian masses. These tumours are part of the sex cord–gonadal stromal tumour or non-epithelial group of tumours.
It shows the typical features of invasive breast cancer with infiltrative growth pattern, here including invasion into adipose tissue and with an associated fibrous or desmoplastic stromal response. It has the criterion of more than 90% of the tumor composed of small, ovoid or angulated tubules with open lumina.
Microcystic carcinoma 11% [5] Cystic dilatation and rounded expansion of malignant glands [6] Lined by flat cells [6] Intraluminal crystalloids, and wispy blue intraluminal mucin [6] 34βE12- and p63-[6] AMACR+ [6] On (usually) adjacent acinar adeocarcinoma [6] PIN-like 1.3% [7] Glands lined by ≥2 layers of malignant cells [1]