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Polysorbate 20, a compound used as a food additive in some pudding mixes to prevent scorching during preparation. Polysorbates are a class of emulsifiers used in some pharmaceuticals and food preparation. They are commonly used in oral and topical pharmaceutical dosage forms.
Polysorbate 80 is a surfactant and solubilizer used in a variety of oral and topical pharmaceutical products. Polysorbate 80 is also an excipient that is used to stabilize aqueous formulations of medications for parenteral administration, and used as an emulsifier in the making of the antiarrhythmic amiodarone . [ 9 ]
The following is a list of chemicals published as a requirement of Safe Drinking Water and Toxic Enforcement Act of 1986, commonly known as California Proposition 65, that are "known to the state to cause cancer or reproductive toxicity" as of January 3, 2020. [1]
Polysorbate 20 – emulsifier; Polysorbate 40 – emulsifier; Polysorbate 60 – emulsifier; Polysorbate 65 – emulsifier; Polysorbate 80 – emulsifier; Polyvinylpolypyrrolidone – color stabiliser; Pomegranate seeds (though some consider these a fruit, not a spice) – Ponceau 4R – color (FDA: Ext D&C Red #8) Ponceau 6R – color; Ponceau ...
Coating these polymeric nanoparticle devices with different surfactants can also aid BBB crossing and uptake in the brain. Surfactants such as polysorbate 80, 20, 40, 60, and poloxamer 188, demonstrated positive drug delivery through the blood–brain barrier, whereas other surfactants did not yield the same results. [2]
Sorbitan is produced by the dehydration of sorbitol and is an intermediate in the conversion of sorbitol to isosorbide.The dehydration reaction usually produces sorbitan as a mixture of five- and six-membered cyclic ethers (1,4-anhydrosorbitol, 1,5-anhydrosorbitol and 1,4,3,6-dianhydrosorbitol) [3] with the five-membered 1,4-anhydrosorbitol form being the dominant product.
Vaccine Excipients Adenovirus vaccine: This list refers to the type 4 and type 7 adenovirus vaccine tablets licensed in the US: Acetone, alcohol, anhydrous lactose, castor oil, cellulose acetate phthalate, dextrose, D-fructose, D-mannose, FD&C Yellow #6 aluminium lake dye, fetal bovine serum, human serum albumin, magnesium stearate, micro crystalline cellulose, plasdone C, Polacrilin potassium ...
Polysorbate 20 is used by philatelists to remove stamps from envelopes and to remove residues from stamps, without harming the stamp itself. Polysorbate 20 is also used as wetting agent in rubber balers in the elastomer industry. Polysorbate 20 has been used as a shape directing agent to synthesize spheroidal magnetite nanoassemblies. [5]