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Sebaceous adenomais a type of adenoma, characterized by a slow-growing tumor usually presenting as a pink, flesh-coloured, or yellow papule or nodule. [ 1 ] : 662 [ 2 ] Significance
Adenoma sebaceum presence represents one of the major diagnostic criteria to confirm the diagnosis of tuberous sclerosis. [5] When adenoma sebaceum presents with seizures and mental retardation (Vogt's triad), it indicates that cranial imaging is necessary, other differential diagnoses for this disorder include acne vulgaris, rhinophyma, and sebaceous hyperplasia.
Somatotrophic adenomas have only been described in two dogs. [1] In 1996 a 9 year old male Doberman Pinscher with difficult to manage diabetes mellitus but no signs of acromegaly was euthanised. Necropsy later revealed an acidophilic adenoma with immunohistochemical staining for growth hormone, adrenocorticotropic hormone, and prolactin. [6]
Melanomas* account for four to six percent of skin tumors in dogs and are usually benign. They are the second most common tumor of the toe and are malignant in this location. Malignant melanoma is also a common oral tumor in dogs. Malignant tumors most commonly spread to the lymph nodes and lungs. [165]
Sebaceoma is a smooth-bordered, plump, well-circumscribed benign tumor that may expand into the subcutis, middle dermis, and deep dermis. Lesions range in size from tiny lesions to 20 mm. Clinically, the tumor appears as a single flesh-colored or erythematous nodule or plaque in the head and neck region.
Sebaceous adenitis is an uncommon skin disease found in some breeds of dog, and more rarely in cats, rabbits and horses. [ 1 ] characterised by an inflammatory response against the dog's sebaceous glands (glands found in the hair follicles in the skin dermis ), which can lead to the destruction of the gland.
The distinction may be moot because both entities have the same treatment, although the adenoma has a greater growth potential. Sebaceous carcinoma of the oral cavity has been reported, presumably arising from Fordyce granules or hyperplastic foci of sebaceous glands. [citation needed]
Fibrous papules are also termed facial angiofibromas and were formerly and incorrectly termed adenoma sebaceum (fibrous papules are unrelated to sebaceous glands [4]). They develop in up to 8% of the general adult population and occur as 1 to 3 [5] pink to red, [4] dome-shaped papules in the central areas of the face, nose, and/or lips. [6]