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A vitamin D blood-concentration standard for diagnosing hypovitaminosis D does not exist. In the past, hypovitaminosis D was defined by blood concentrations lower than 20 ng/mL. [ 6 ] However, in more recent literature many researchers have considered 30 ng/mL to be an insufficient concentration of vitamin D. [ 6 ] Subnormal levels of vitamin D ...
Mapping of several bone diseases onto levels of vitamin D (calcidiol) in the blood [6] Normal bone vs. osteoporosis. Vitamin D deficiency is typically diagnosed by measuring the concentration of the 25-hydroxyvitamin D in the blood, which is the most accurate measure of stores of vitamin D in the body.
Vitamin D activation occurs in the kidney. PTH up-regulates 25-hydroxyvitamin D 3 1-alpha-hydroxylase, the enzyme responsible for 1-alpha hydroxylation of 25-hydroxy vitamin D, converting vitamin D to its active form (1,25-dihydroxy vitamin D). This activated form of vitamin D increases the absorption of calcium (as Ca 2+ ions) by the intestine ...
Vitamin D is believed to help with bone density, especially when it’s paired with calcium, Segil says. When you add in exercise, it can create a big boost for your bone health .
In adults, vitamin D, together with calcium, can help prevent osteoporosis, which causes bones to become weak and brittle, increasing the risk of fractures, TODAY.com previously reported.
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