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In addition to tremors, lithium treatment appears to be a risk factor for development of parkinsonism-like symptoms, although the causal mechanism remains unknown. [73] In the average bipolar patient, chronic lithium use is not associated with cognitive decline. [74] Most side effects of lithium are dose-dependent.
Treatment was initiated at 0.125 mg thrice daily and increased at a rate of 0.125 mg thrice daily to a limit of 4.5 mg per day until the patients' condition satisfactorily responded to the medication or they could not abide the side effects. The final average dosage was 1.7 mg ± 0.90 mg per day.
Bipolar disorder is a long-term mood disorder characterized by major ... especially treatment with the mood stabilizer lithium. ... Some common side effects of bipolar medications include weight ...
Lithium is preferred for long-term mood stabilization. [68] Lithium treatment is also associated with adverse effects and it has been shown to erode kidney and thyroid function over extended periods. [17] Valproate has become a commonly prescribed treatment and effectively treats manic episodes. [147]
Lithium toxicity, also known as lithium overdose, is the condition of having too much lithium. Symptoms may include a tremor, increased reflexes, trouble walking, kidney problems, and an altered level of consciousness .
Medications are used to reverse the symptoms of extrapyramidal side effects caused by antipsychotics or other drugs, by either directly or indirectly increasing dopaminergic neurotransmission. The treatment varies by the type of the EPS, but may involve anticholinergic agents such as procyclidine, benztropine, diphenhydramine, and trihexyphenidyl.