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  2. Necrosis - Wikipedia

    en.wikipedia.org/wiki/Necrosis

    Necrosis (from Ancient Greek νέκρωσις (nékrōsis) 'death') is a form of cell injury which results in the premature death of cells in living tissue by autolysis. [1] The term "necrosis" came about in the mid-19th century and is commonly attributed to German pathologist Rudolf Virchow , who is often regarded as one of the founders of ...

  3. Caseous necrosis - Wikipedia

    en.wikipedia.org/wiki/Caseous_necrosis

    As the cells die they disintegrate but are not completely digested and the debris of the disintegrated cells clump together creating soft granular mass that has the appearance of cheese. [9] As cell death begins, the granuloma forms and cell death continues the inflammatory response is mediated by a type IV hypersensitivity reaction. [10]

  4. Cell death - Wikipedia

    en.wikipedia.org/wiki/Cell_death

    Overview of signal transduction pathways involved in apoptosis. Cell death is the event of a biological cell ceasing to carry out its functions. This may be the result of the natural process of old cells dying and being replaced by new ones, as in programmed cell death, or may result from factors such as diseases, localized injury, or the death of the organism of which the cells are part.

  5. Identification of cell death - Wikipedia

    en.wikipedia.org/wiki/Identification_of_cell_death

    The role of cell death is the maintenance of tissue and organ homeostasis, for example, the regular loss of skin cells or a more active role seen in involuting tissues like the thymus. Cells die either by accident or design. In fact there are two mechanisms of cell death; necrosis and apoptosis (apoptosis in invertebrates is called cell ...

  6. Coagulative necrosis - Wikipedia

    en.wikipedia.org/wiki/Coagulative_necrosis

    Coagulative necrosis is a type of accidental cell death typically caused by ischemia or infarction. In coagulative necrosis, the architectures of dead tissue are preserved for at least a couple of days. [1] It is believed that the injury denatures structural proteins as well as lysosomal enzymes, thus blocking the proteolysis of the damaged cells.

  7. Ischemic cell death - Wikipedia

    en.wikipedia.org/wiki/Ischemic_cell_death

    Ischemic cell death, or oncosis, is a form of accidental cell death.The process is characterized by an ATP depletion within the cell leading to impairment of ionic pumps, cell swelling, clearing of the cytosol, dilation of the endoplasmic reticulum and golgi apparatus, mitochondrial condensation, chromatin clumping, and cytoplasmic bleb formation. [1]

  8. Multiple myeloma - Wikipedia

    en.wikipedia.org/wiki/Multiple_myeloma

    EBV-positive disease is more common in the plasmacytoma rather than multiple myeloma form of plasma cell cancer. [46] Tissues involved in EBV+ disease typically show foci of EBV+ cells with the appearance of rapidly proliferating immature or poorly differentiated plasma cells. [46] The cells express products of EBV genes such as EBER1 and EBER2 ...

  9. Sarcoma - Wikipedia

    en.wikipedia.org/wiki/Sarcoma

    [1] [2] Connective tissue is a broad term that includes bone, cartilage, muscle, fat, vascular, or other structural tissues, and sarcomas can arise in any of these types of tissues. [2] [3] As a result, there are many subtypes of sarcoma, which are classified based on the specific tissue and type of cell from which the tumor originates. [4]